Thursday, January 25, 2018

A Magic Pill for ME/CFS?

Isn't there a drug or drugs for ME/CFS?

Unfortunately, there's currently no magic pill for this devastating illness. I wish there was!


But with the exception of some specific antibiotics, antifungals or antivirals, for the most part, drugs have not been the answer for patients withe ME/CFS. 

Thanks to a recent groundbreaking study, we now know why -- a great many of them interfere with mitochondrial (cellular energy) function, which is the last thing we need.

According to the study's lead author, Robert Naviaux:
"Many antibiotics like tetracyclines, erythromycin, and the fluoroquinolones (eg, Cipro), and antivirals like acyclovir, fialuridine, AZT, and ddC also inhibit mitochondrial functions when used chronically (usually for more than about 3 weeks). Chronic use of these drugs can do more harm than good if there is no longer good evidence for an active infection. When mitochondrial functions are critically impacted by long-term use of certain antibiotics, a ripple effect in metabolism and gene expression is produced that can further impair energy production by mitochondria, converting an active cell danger response that occurs during active infection to a hypometabolic survival response."
Now maybe someday there will be a 'magic pill' -- there's certainly a lot of great research going on lately* -- but I'm not holding my breath. I can't afford to. If something should show real promise, it will still require several clinical trials and thus probably take at least 10 years to get approved by the FDA. 

Instead, I need to follow the path that others I know have used and are using, and that's an integrative approach, working along with the doctor who helped stop my decline. 

*Above, the team of scientists from all around the world, brought together this past August by the great Ron Davis at the Open Medicine Foundation’s Community Symposium on the Molecular Basis of ME/CFS


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